Search results

Looks like it was translated from Russian to English. "Allocate methcatinone" here means "You can stop at this point if you want to get methcatinone" "Reverse refrigerator" means "Reflux condenser" Also before addition of Na borohydride it is good idea to make sure RM has no water in it.

In terms of obtaining PMK there is no difference. Both are esters, both will convert to the same product

To be honest you can use 25% methylamine in water just recalculate the amount you need for the reaction. If your reaction requires 50% then just use twice aamount of 25% If however you need 40% or higher amount you can do this: put small amount (50-100gm) of methylamine hydrochloride in the...

Why do you think this method gives you 50% methylamine? You are using approx 7.45 mol of methylamine HCL which after basification will yeld 7.45 mol of methylamine gas which is approx 232g dissolved in 1134ml of water. It is far from 50%. The reaction itself produces 7.45mol of water in addition...

The link you provided above uses Diethyl(phenylacetyl)malonate for conversion to P2P but this thread is about Diethyl phenylmalonate. I am a bit confused. Could be diethylphenylmalonate be used for conversion to P2P? Just use it instead of phenylacetyl or what?

i made it before via perborate route. yelds however are low, workup is messy, requires a gas generator. bayer-villager reaction tends to runaway at big loads and requires temperature control (too cold= solidifies, too hot = peracid fumes everywhere and boiling). just wanted to try something new...

Most confusing thread I have ever read. So to summarize: It is better to use big excess of phosphoric acid and heat to 110 C to prevent incomplete reaction. Strong stirring is essential. Do we need to add some alcohol to the RM to prevent 2-phase formation?

Original twodogs procedure uses perboric acid made in-situ from acetic acid & sodium perborate. Perboric route is a bit messy and requires filtering

Thats insane amount of acetonitrile. Can it be substituted?