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Ok, isatin derivate, not indandione. Cool paper. You probably forget to add N in structure editor.

This reaction isn't used for required piperidone, maybe because of self condensation and mix of products, when formaldehyde used instead of benzaldehyde, steric hindrance is important too. I saw many papers, and piperidones or 4-substituted piperidines was made through: acrylates, organosilicon...

double posted

What's in the RC section? I would like to see. I saw almost any drug structure since research chemicals was appeared, i think i will see something what i saw before.

There is a mistake? Where you got second nitrogen in the last stage on the picture? Can you tell the source of this work?

It must be cathinone, a-pvp like. Is it smells like cum or chlorine, when vaped? What the melting point of this substance?

What ? This is not a drug, and its must be toxic.

Oh no, whats happened? I don't like this style, can i change it?

Can last stage be completed with methyl iodide? Or what can i use instead of dimethyl sulfate? How dimethylsulfate is can be made in home lab?

up the questions

Its an old cannabinoids, you probably won't get it anywhere. But in some countries precursors can be legal.

How cocaine is made? Its just alkaloid extraction, or some labs works with tropane derivates? I'm interested in synthetic cocaine, how to purify exact isomer? Synthetic cocaine is real or not? Can cartels behead me if i'll do that?

Probably, a new bestseller with high potency and long lasting effects. Dangerous shit! 200x potency of morphine and ~3 hrs of action. (WARNING: OPIOID USE GLORIFY SHIT, I WARNED YOU) https://etometh.info/ Etomethazene, appeared on drug market in the 2022 spring. (methyl instead of nitro group...

Great! Much easier than fent, i want to try this. Although, it's required more safety on last stage. With fent you just add anhydride to anpp (also toxic, but much weaker than any fent derivate) and then you can easily transfer yield directly to diluting agent, without contamination. And burn...

Interesting and frustrating! What do you know about drug ***** in China? With this wide range of very cheap synthetic drugs they must be high 24/7, but seems not.

2-bromo-4-methylpropiophenone for $20-30? Very cheap, It's a goldmine! How they're shipping it? 4-methylpropiophenone smells very strong, i don't want to be listed as a clandestine chemist. But damn, i want it. How they're making it, which route makes it too cheap (both, 2-bromo and plain ketone)?

Reaction with calcium carbonate makes a lot of foam. Once i did it, i failed. But maybe try it again.

If you need 4-piperidone itself, not ANPP or NPP, you probably will be able to do it only by N-benzyl amine route through acrylates. And later removing benzyl by hydrogenation on palladium. I think, easier routes should be known. Maybe it possible to make boc salt of pyridine derivate like...

Nice goods! Looks like the distribution is a main problem, and money laundering. Not chemistry. I'm not a criminal, but would like to see some advice how it should work in modern days to avoid law enforcement with high tech equipment and eyes everywhere. Bitcoin blockchain isn't anonymous, for...

If you on way to dmt through reduction, it should give MIPT, but fraction will be very low. It's obviously, any ketone react in that way even in small ammounts.