Search results

  1. J

    Synthesis of Desoxypipradrol

    pyridine alpha arylation of diphenylacetonitrile under phase transfer conditions; https://sci-hub.hkvisa.net/https://doi.org/10.1016/S0960-894X(01)00443-7
  2. J

    Synthesis of Desoxypipradrol

    The original synthesis of Desoxypipradrol as written in the patent linked below is effected by the condensation of Diphenyl acetonitrile with 2 Bromo pyridine followed by hydrolysis of the nitrile and decarboxylation and then catalytic hydrogenation of the pyridine ring with Raney Nickel. A...
  3. J

    Phenylacetone (P2P) synthesis from benzaldehyde with butanone

    It is not a catalyst it is an oxidant please read the link provided, search up baeyer villiger oxidation.
  4. J

    Benzaldehyde synthesis from benzyl alcohol. 1 kg Scale.

    https://sci-hub.yncjkj.com/10.1055/s-0037-1609149
  5. J

    Phenylacetone (P2P) synthesis from benzaldehyde with butanone

    https://sci-hub.hkvisa.net/https://doi.org/10.1016/j.forsciint.2016.03.034
  6. J

    Substituting solvents in a benzaldehyde oxidation.

    I have found a promising research paper: https://sci-hub.hkvisa.net/https://doi.org/10.1081/SCC-120005418 It uses acetonitrile as co solvent, I would much rather use N methyl pyrrolidone, https://sci-hub.hkvisa.net/10.1002/047084289X.rm240.pub2 Do think think that the reaction will fail?
  7. J

    Benzaldehyde solubility in organic solvents.

    Do any chemists here have information pertaining to the solubility of benzaldehyde in a variety of organic solvents like dimethyl formamide, dimethyl sulfoxide, acetonitrile, N methyl pyrrolidone? If I find any information relevant to this question I will post it below.
  8. J

    Synthesis of (s)-cathinone from N-acetyl-L-alanine

    https://chemistry.mdma.ch/hiveboard/rhodium/pdf/fc-acylation.n-carbamyl-alpha-amino-acyl-chlorides.pdf
  9. J

    Leuckart amination help

    Here is the pdf.
  10. J

    Leuckart amination help

    Search up M. B. Tolmie Masters Thesis - Australian Federal Police, it is a pdf related to the leukart reaction. https://www.sciencemadness.org/talk/viewthread.php?tid=144546&page=3
  11. J

    Synthesis of (s)-cathinone from N-acetyl-L-alanine

    William can you tell me if carbamyl groups are labile under friedel crafts conditions because it is known that carbamate esters are reduced to the N alkyl group upon reduction for example the methyl carbamate (S)-methyl (1-phenylpropan-2-yl)carbamate would be reduced to (S) methamphetamine, it...
  12. J

    Questions regarding new route to Phenyl acetone, from ramberg Backlund reaction.

    While reading Erowid (https://erowid.org/archive/rhodium/chemistry/phenylacetone.html) A pathway stood out which was a wittig reaction between benzaldehyde and the triphenylphosphonium salt of alpha chloro ethyl methyl ether, the product of this reaction is an enol methyl ether which can be...
  13. J

    A synthesis of enantiopure substituted Trans 4 Methylaminorex. And indane analogs.

    There is prevailing interest in 4 Methylaminorex and its derivatives, in part owning to it's scarcity. Pharmacological study's suggest that the rank order of potencies for 4 Methylaminorex enatiomers is trans-4S,5S > cis-4S,5R ~ cis-4R,5S > trans-4R,5R and racemic Trans methylaminorex is...
  14. J

    Any questions?

    What has motivated you to make this forum?
Top