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  1. M

    Questions regarding alprazolam/flualprazolam synthesis

    Thank you for the help! I am unsure over the ethyl chloroacetate, but I strongly believe the acetyl chloride should work in place of acetic anhydride - it is a LOT more reactive, but hopefully not too much. Anyway, due to how easy it is to get acetyl chloride here, it's only a quick reaction...
  2. M

    Questions regarding alprazolam/flualprazolam synthesis

    Thank you for the reply! In regards to the acetyl chloride, are you suggesting that it should work? I'm a little confused with your answer in that regard. I'll do some more research into the ethyl chloroacetate substitution, as it's definitely easier to get ahold of. I did mean an RBF...
  3. M

    Questions regarding alprazolam/flualprazolam synthesis

    My reference material is 10.1007/s00044-016-1585-z and the small scale alprazolam synthesis that I found here - I do understand the basic process. I do have a few questions though, and can't really find answers to them online elsewhere. The precursor of 2-amino-5-chlorobenzophenone is for...
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