Melantonan 2 (Pt-141)

[Olaf2]

I am interested in the peptide pt-141 and how to get hold of it or how to synthesize it.

Does anyone have a plan?

 

[brzipostar]

It's important to have a solid understanding of peptide chemistry. There are some resources online, but be cautious about sourcing materials.

 

[HerrHaber]

"solution phase synthesis of the cyclic heptapeptide melanotan II in 2.6% overall yield for 12 steps"

The first preparative solution phase synthesis of melanotan II

Melanotan II is a synthetic cyclic heptapeptide used to prevent a sunlight-induced skin cancer by stimulating the skin tanning process. In this paper we report the first solution phase synthesis of the title compound. The hexapeptide sequence ...

www.ncbi.nlm.nih.gov